PTMOracle Visualize PTMs !!! in Protein Protein Interaction data!!
PTMOracle Visualize PTMs !!! in Protein Protein Interaction data!! I dont have proof yet that this is as good as I think it might be. If it is, this is a serious missing link in proteomics filled in (courtesy of free software!!!) What I might be ridiculously excited about is the PTMOracle, which you can read about in this new JPR paper here. If you start doing any kind of PTM study and want to move to downstream analysis you will quickly find you need to: 1) Hijack some genomics tools built years ago for microarrays 2) Use some genomics tools someone hijacked years ago for microarrays and made kinda good at proteomics (and available) 3) Do lots and lots of manual work Those genomics tools are awesome. They really are. On the downstream analysis/data processing end, theyve got a 10 year head start on us. But -- upregulation of the entire ERK protein may do something very different in a cell than ERK phosphorylation on the normal active tyrosine (or the less common, biologically, but eas...